內容簡介 Incorporating the most important advances in the rapidly-evolving field of cancer biology, this book remains the defining course text on its subject. Students, instructors, researchers, and clinicians the world over admire its authoritative content, clear explanations, extensive full-color art program, and pedagogical features that promote a deep conceptual understanding of the science through the lens of fascinating tales of scientific discovery. 目次 Chapter 1: The Biology and Genetics of Cells and Organisms Chapter 2: The Nature of Cancer Chapter 3: Cancer as an Infectious Disease Chapter 4: Cellular Oncogenes Chapter 5: Growth Factors, Receptors, and Cancer Chapter 6: Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer Chapter 7: Tumor Suppressor Genes Chapter 8: pRb and Control of the Cell Cycle Clock Chapter 9: p53: Master Guardian and Executioner Chapter 10: Eternal Life: Cell Immortalization and Tumorigenesis Chapter 11: Multi-Step Tumorigenesis Chapter 12: Shaping and Characterizing the Cancer Genome Chapter 13: Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis Chapter 14: Moving Out: Invasion and Metastasis Chapter 15: Crowd Control: Tumor Immunology Chapter 16: Cancer Immunotherapy Chapter 17: The Rational Treatment of Cancer Supplementary Sidebars