Chemical Sensors and Biosensors

Technological needs for chemical, ionic and biological species detection are giving rise to continuous research and development in physico-chemistry and biology. The constant progress being made in the theoretical and technological aspects concerning studies and developments of chemical sensors, biosensors and biochips is presented in this book by different scientists and professors from different universities and constitutes an updating of the state of the art for chemical sensors, biosensors and biochips. This book places a large emphasis on interaction between chemical and biological species, in a gaseous or liquid state, and details mineral and biological materials acting as sensitive elements. The role of electrical, electrochemical, piezoelectric and optical transducers in detection mechanisms are presented through their developments and from a performance point-of-view. Micro-reactors, nanotechnologies and flexible substrates, are considered in relation to their role in neural networks.

Preface xv Chapter 1. Chemical and Biological Recognition 1 Nicole JAFFREZIC-RENAULT Chapter 2. Adsorption Phenomena 27 René LALAUZE Chapter 3. Microcantilever Transduction 49 Isabelle DUFOUR Chapter 4. Piezoelectric Transduction (QCM) 71 Hubert PERROT Chapter 5. Metal Oxide Gas Sensors 93 Christophe PIJOLAT Chapter 6. Molecular Material-based Conductimetric Gas Sensors 127 Marcel BOUVET Chapter 7. Responses and Electrical Properties of Gas Microsensors 143 Khalifa AGUIR Chapter 8. Gas Microsensor Technology 175 Philippe MENINI Chapter 9. Multisensors: Measurements and Behavior Models 211 Philippe BREUIL Chapter 10. Development of Microtechnologies for the Realization of Chemical, Biochemical and/or Biological Microsensors 235 Pierre TEMPLE-BOYER Chapter 11. Development of Micro-preconcentrators for the Detection of Gaseous Species at Trace Level 261 Jean-Paul VIRICELLE Chapter 12. Microfluidics: Manipulation of Nanovolume Samples 293 Louis RENAUD Chapter 13. Electrochemical Biosensors 313 Chantal GONDRAN Chapter 14. Fiber-optic Biosensors 335 Neso SOJIC Chapter 15. In Vivo Analyses with Electrochemical Microsensors 353 Stéphane ARBAULT Chapter 16. Microbial Biosensors for Environmental Applications 373 Gérald THOUAND and Marie José DURAND Chapter 17. Biofuel Cells 409 Serge COSNIER List of Authors 425 Index 427