One Health

Emerging infectious diseases are often due to environmental disruption, which exposes microbes to a different niche that selects for new virulence traits and facilitates transmission between animals and humans. Thus, health of humans also depends upon health of animals and the environment – a concept called One Health. This book presents core concepts, compelling evidence, successful applications, and remaining challenges of One Health approaches to thwarting the threat of emerging infectious disease. Written by scientists working in the field, this book will provide a series of "stories" about how disruption of the environment and transmission from animal hosts is responsible for emerging human and animal diseases. Explains the concept of One Health and the history of the One Health paradigm shift. Traces the emergence of devastating new diseases in both animals and humans. Presents case histories of notable, new zoonoses, including West Nile virus, hantavirus, Lyme disease, SARS, and salmonella. Links several epidemic zoonoses with the environmental factors that promote them. Offers insight into the mechanisms of microbial evolution toward pathogenicity. Discusses the many causes behind the emergence of antibiotic resistance. Presents new technologies and approaches for public health disease surveillance. Offers political and bureaucratic strategies for promoting the global acceptance of One Health.

Contributors Preface One Health: What Is It and Why Is It Important? 1. Combating the Triple Threat: The Need for a One Health Approach 2. The Value of the One Health Approach: Shifting from Emergency Response to Prevention of Zoonotic Disease Threats at Their Source    3. The Human-Animal Interface 4. Ecological Approaches to Studying Zoonoses 5. Emerging Infectious Diseases of Wildlife and Species Conservation Zoonotic and Environmental Drivers of Emerging Infectious Diseases 6. RNA Viruses: A Case Study of the Biology of Emerging Infectious Diseases 7. Factors Impacting the Control of Rabies 8. Emergence of Influenza Viruses and Crossing the Species Barrier   9. One Health and Food-Borne Disease: Salmonella Transmission between Humans, Animals, and Plants 10. Cholera: Environmental Reservoirs and Impact on Disease Transmission 11. White-Nose Syndrome: Human Activity in the Emergence of an Extirpating Mycosis One Health and Antibiotic Resistance 12. Antibiotic Resistance in and from Nature Disease Surveillance 13. Public Health Disease Surveillance Networks 14. Web-Based Surveillance Systems for Human, Animal, and Plant Diseases 15. Genomic and Metagenomic Approaches for Predicting Pathogen Evolution 16. Surveillance of Wildlife Diseases: Lessons from the West Nile Virus Outbreak Making One Health a Reality 17. Defining the Future of One Health 18. Making One Health a Reality—Crossing Bureaucratic Boundaries 19. One Health: Lessons Learned from East Africa 20. The Future of One Health Index