Population Genetics and Microevolutionary Theory

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Preface ix 1. Scope and Basic Premises of Population Genetics 1 Part I. Population Structure and History 19 2. Modeling Evolution and The Hardy–Weinberg Law 21 3. Systems of Mating 48 4. Genetic Drift 82 5. Genetic Drift In Large Populations and Coalescence 118 6. Gene Flow and Population Subdivision 168 7. Gene Flow and Population History 204 Part II. Genotype and Phenotype 247 8. Basic Quantitative Genetic Definitions and Theory 249 9. Quantitative Genetics: Unmeasured Genotypes 274 10. Quantitative Genetics: Measured Genotypes 297 Part III. Natural Selection and Adaptation 341 11. Natural Selection 343 12. Interactions of Natural Selection With Other Evolutionary Forces 372 13. Units and Targets of Selection 407 14. Selection In Heterogeneous Environments 453 15. Selection In Age-Structured Populations 497 Appendix 1. Genetic Survey Techniques 540 Appendix 2. Probability and Statistics 555 References 582 Problems and Answers 612 Index 681