Unravelling Long COVID

Unravelling Long COVID An authoritative medical reference on the various ways in which Long-COVID presents and an in-depth discussion of its mechanisms and potential therapeutic options. Unravelling Long COVID aims to provide a better awareness and understanding of the persistent health problems that can arise following SARS-CoV-2 infection. Variously described as Long-COVID, Long-Haulers’ Syndrome, and Post-Acute Sequelae of SARS-CoV-2, this newly-designated disorder is estimated to have affected somewhere between 50 to 250 million people. It is in fact considered by many as the next global public health disaster. With such a broad and important topic, the authors of Unravelling Long COVID have focused primarily on two major problems in the current understanding of Long-COVID: 1.) the failure to distinguish patients with organ damage—here called Long-COVID Disease – and those with unexplained, persistent symptoms—what is termed Long-COVID syndrome, and 2.) the failure of current medical approaches to comprehend and treat those persistent unexplained symptoms. Unravelling Long COVID is: One of the first books focused specifically on defining and understanding Long-COVID with the goal of establishing optimal management A unique reference to distinguish patients with organ damage caused by Long-COVID disease from those with unexplained, persistent symptoms that manifest as Long-COVID syndrome An in-depth exploration of neuroimmune pathways to help clarify the previously unexplained symptoms of Long-COVID Unravelling Long COVID is an essential reference for anyone interested in Long-COVID and the impact that this condition has had on the population. It will be a useful resource for both patients suffering from the Long-Covid syndrome, their physicians and for the growing number of Long-COVID clinics that have been established across the US, the UK, and other countries.

Introduction Section 1: Long-COVID Disease Chapter 1. Long-COVID Disease or Long-COVID Syndrome?  Chapter 2. Lung, Heart Disease, and Other Organ Damage Chapter 3. COVID-19 Direct Effects on the Central Nervous System Section 2: Long-COVID Syndrome and Unexplained Symptoms Chapter 4. Unexplained Symptoms: Medicine’s Blind Spot Chapter 5. Historical Perspectives, Including Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Fibromyalgia Section 3. Mechanisms and Pathways Chapter 6. Brain Homeostasis Run Amok Chapter 7. Neuroimmune Dysfunction Section 4. Evaluation and Management Chapter 8. Patient Evaluation and Research Chapter 9. Patient Management and Rethinking Healthcare Amid Long COVID Chapter 10. The Way Forward: For Patients, Healthcare Providers, and Research Appendix A. Long-COVID Clinics in the US and Europe Appendix B. Suggestions for Future Research Focused on the Cellular and Molecular Basis of Long-COVID Syndrome Index