The New Prescriber

Take an evidence-based approach to prescribing decisions with this comprehensive guide Prescribing decisions are among the most important parts of clinical practice. Balancing patient needs, possible drug interactions, the probability of adverse drug reactions, and more requires an evidence-based approach rooted in pharmacological principles. The New Prescriber: An Integrated Approach to Medical and Non-medical Prescribing offers a thorough, accessible introduction to the core components of prescribing, essential for any student preparing for clinical practice. Now fully updated to reflect the latest best practices and to address questions raised by different prescribing settings, it promises to continue as the key introduction to this vital subject. Readers of the second edition of The New Prescriber will also find: An introduction to the principles of pharmacodynamics and pharmacokinetics New sections covering topics including illegal and illicit drugs, overdose and deprescribing, and more A thorough glossary with key terms The New Prescriber is ideal for all non-medical prescribing students, nursing, allied health professionals, and medical students.

List of Contributors xxvi Foreword xxvii Preface xxviii Acknowledgements xxix Section 1 The Patient 1 Section Introduction 1 1 The Consultation 3 Frank Coffey and Dianne Bowskill 2 Accountability and Prescribing 14 Matthew Boyd, Stephanie Bridges, and Helen Boardman 3 Prescribing and the Law 23 Richard Griffith 4 The Ethics of Prescribing 36 Matthew Boyd, Stephanie Bridges, and Helen Boardman 5 Prescribing in Practice 44 Dianne Bowskill and Daniel Shipley 6 Public Health Issues 53 Michael Watson and Katharine Whittingham Section 2 Pharmacology 63 Section Introduction 65 7 General Principles of Pharmacology 67 Joanne Lymn and Alison Mostyn 8 Pharmacokinetics 1: Absorption and Distribution 79 Joanne Lymn and Alison Mostyn 9 Pharmacokinetics 2: Metabolism and Excretion 92 Joanne Lymn and Alison Mostyn 10 Routes of Administration 106 Joanne Lymn and Roger Knaggs 11 Variations in Drug Handling 114 Michael Randall 12 Polypharmacy and Medicines Optimisation 124 Daniel Shipley 13 Adverse Drug Reactions and Interactions 134 Alison Mostyn and Daniel Shipley 14 Introduction to the Autonomic Nervous System 144 Joanne Lymn 15 Clinical Application of the Principles of the Autonomic Nervous Systems 157 Joanne Lymn 16 The Gastrointestinal System 167 Michael Randall 17 Cardiovascular Drugs and Diseases 177 Richard Roberts 18 Haemostasis and Thrombosis 196 Michael Randall 19 The Renal System 208 Michael Randall 20 The Respiratory System 221 Richard Roberts 21 Introduction to the Central Nervous System 235 Yvonne Mbaki 22 Neurodegenerative Disorders 245 David Kendall 23 Depression and Anxiety 256 Yvonne Mbaki 24 Schizophrenia 267 David Kendall 25 Epilepsy and Antiseizure Drugs 277 Michael F O’Donoghue and Christina Giavasi 26 Pain and Analgesia 293 Roger Knaggs 27 Drugs of Misuse 308 Michael Randall 28 Antibacterial Chemotherapy 315 Tim Hills 29 Antibiotic Resistance and Clostridioides Difficile 331 Tim Hills 30 Antifungal and Antiviral Drugs 342 Tim Hills 31 The Endocrine System 352 Alison Mostyn and Daniel Shipley 32 Contraception and Reproductive Health 369 Alison Mostyn and Anna Soames 33 Cancer Pharmacotherapy 381 Michael Randall 34 Musculoskeletal Disease 392 Sana Awan and David Andrew Walsh Glossary 409 Activity Answers 417 Index 445