Engineered Carbohydrate-Based Materials for Biomedical Applications

This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.

Preface vii Contributors xi 1 Synthesis of Glycopolymers 1 Samuel Pearson, Gaojian Chen, and Martina H. Stenzel 2 Block Glycopolymers and Their Self-assembly Properties 119 Qian Yang 3 Cationic Glycopolymers 143 Marya Ahmed and Ravin Narain 4 Glycopolymer Bioconjugates 167 Marya Ahmed and Ravin Narain 5 Glycopolymer-functionalized Carbon Nanotubes 189 Marya Ahmed and Ravin Narain 6 Glyconanoparticles: New Nanomaterials for Biological Applications 213 Isabel García, Juan Gallo, Marco Marradi, and Soledad Penadés 7 Glycodendrimers and Their Biological Applications 261 Elizabeth R. Gillies 8 Glycosurfaces 307 Anca Mateescu and Maria Vamvakaki 9 Carbohydrate-derived Hydrogels And Microgels 337 Mitsuhiro Ebara 10 Modified Natural Polysaccharides as Nanoparticulate Drug Delivery Devices 355 Archana Bhaw-Luximon Index 397