Inductively Coupled Plasma Mass Spectrometry Handbook

Since the first reported linking of an Inductively Coupled Plasma (ICP) ion source with a mass spectrometer (MS) in 1983, the instrumentation and analytical techniques have been developed to a point where the technology can deliver detection limits of one part in 10^15. With this level of detection, ICP-MS is an invaluable tool in a huge range of applications. Development of the technology continues, for example with the application of lasers to allow direct analysis of solid samples and with linkages to liquid chromatography apparatus for elemental speciation studies, further opening up the scope for this highly sensitive analytical technique.Despite widespread interest and usage, little has been written to describe the analytical techniques and instrumentation in a format accessible to both new and experienced users of the technique. The aim of this book is, therefore, to provide a thorough description of ICP-MS instrumentation and techniques, giving the reader sufficient knowledge to approach the technique with confidence.

Chapter 1: Plasma generation, ion sampling and focusing. Chapter 2: Mass spectrometers. Chapter 3: Ion detection, Data Acquisition and Handling. Chapter 4: Calibration strategies and quality assurance. Chapter 5: Liquid sample introduction: Fundamentals and applications of flow injection and electrothermal vaporisation for ICP-MS. Chapter 6: Laser ablation. Chapter 7. Speciation Analysis. Chapter 8: Collision and reaction cells. Chapter 9: ICP-MS Applications.