Basic Cardiac Electrophysiology for the Clinician

This book translates fundamental knowledge in basic cardiac electrophysiology from the bench to the bedside. Revised and updated for its second edition, the text offers new coverage of the molecular mechanisms of ion channel behavior and its regulation, complex arrhythmias, and the broadening roles of devices and ablation. Clear, straightforward explanations are illustrated by plentiful diagrams to make the material accessible to the non-specialist.

Acknowledgments, vii Foreword to the Second Edition by Douglas P. Zipes, ix Foreword to the First Edition by Douglas P. Zipes, xi Introduction, 1 Chapter 1 Bioelectricity, 7 Chapter 2 Ion Channels, 43 Chapter 3 Ion Channel Regulation, 72 Chapter 4 Impulse Initiation and Propagation in Cardiac Muscle, 92 Chapter 5 Rate Dependency of Discontinuous Propagation, 121 Chapter 6 Basic Mechanisms of Cardiac Arrhythmias, 152 Chapter 7 Rotors, Spirals, and Scroll Waves in the Heart, 191 Chapter 8 Rotors and the Mechanisms of Atrial Fibrillation, 224 Chapter 9 Molecular Mechanisms of Ventricular Fibrillation, 254 Chapter 10 Inheritable Arrhythmogenic Diseases, 276 Bibliography, 316 Index, 335