Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.

Contributors xxiv Preface xxxi Part I Introduction 1 1 Novel Omics Technologies in Food Nutrition 3 Xuewu Zhang, Lijun You, Wei Wang, and Kaijun Xiao 2 Seafood Authentication using Foodomics: Proteomics, Metabolomics, and Genomics 14 Karola Böhme, Jorge Barros-Velázquez, Pilar Calo-Mata, José M. Gallardo, and Ignacio Ortea 3 A Foodomics Approach Reveals Hypocholesterolemic Activity of Red Microalgae 31 Irit Dvir, Aliza H. Stark, and Shoshana (Malis) Arad Part II Genomics 41 4 Gene-Diet Interaction and Weight Management 43 Lu Qi 5 NutrimiRomics: The Promise of a New Discipline in Nutrigenomics 53 Amitava Das and Chandan K. Sen 6 Genomics as a Tool to Characterize Anti-inflammatory Nutraceuticals 61 Amitava Das, Scott Chaffee, and Sashwati Roy 7 Nutrigenomics, Inflammaging, and Osteoarthritis: A Review 71 Ali Mobasheri, Richard Barrett-Jolley, Caroline A. Staunton, Chris Ford, and Yves Henrotin 8 Genetic Basis of Anti-Inflammatory Properties of Boswellia Extracts 85 Golakoti Trimurtulu, Chandan K. Sen, Alluri V. Krishnaraju, Kiran Bhupathiraju, and Krishanu Sengupta 9 Cancer Chemopreventive Phytochemicals Targeting NF-κB and Nrf2 Signaling Pathways 102 Hye-Kyung Na and Young-Joon Surh 10 The Beneficial Health Effects of Fucoxanthin 122 Kazuo Miyashita and Masashi Hosokawa 11 Nutrition, Genomics, and Human Health: A Complex Mechanism for Wellness 135 Okezie I. Aruoma 12 Application of Genomics and Bioinformatics Analysis in Exploratory Study of Functional Foods 140 Kohsuke Hayamizu and Aiko Manji 13 Omics Analysis and Databases for Plant Science 150 Masaaki Kobayashi, Hajime Ohyanagi, and Kentaro Yano 14 Synergistic Plant Genomics and Molecular Breeding Approaches for Ensuring Food Security 160 Shouvik Das and Swarup K. Parida 15 Combinatorial Approaches Utilizing Nutraceuticals in Cancer Chemoprevention and Therapy: A Complementary Shift with Promising Acuity 185 Madhulika Singh and Yogeshwer Shukla 16 Nutrigenomic Approaches to Understanding the Transcriptional and Metabolic Responses of Phytochemicals to Diet-Induced Obesity and its Complications 218 Myung-Sook Choi and Eun-Young Kwon 17 Going Beyond the Current Native Nutritional Food Through the Integration of the Omic Data in the Post-Genomic Era: A Study in (Resistant) Starch Systems Biology 230 Treenut Saithong and Saowalak Kalapanulak Part III Proteomics 243 18 Proteomics and Nutrition Research: An Overview 245 Arun K. Tewari, Sudhasri Mohanty, and Sashwati Roy 19 Proteomics Analysis for the Functionality of Toona sinensis 253 Sue-Joan Chang and Chun-Yung Huang 20 Proteomic Approaches to Identify Novel Therapeutics and Nutraceuticals from Filamentous Fungi: Prospects and Challenges 265 Samudra Prosad Banik, Suman Khowala, Chiranjib Pal, and Soumya Mukherjee 21 Proteomics and Metaproteomics for Studying Probiotic Activity 296 Rosa Anna Siciliano and Maria Fiorella Mazzeo 22 Proteomics Approach to Assess the Potency of Dietary Grape Seed Proanthocyanidins and Dimeric Procyanidin B2 304 Hai-qing Gao, Bao-ying Li, Mei Cheng, Xiao-li Li, Fei Yu, and Zhen Zhang 23 Genomic and Proteomic Approaches to Lung Transplantation: Identifying Relevant Biomarkers to Improve Surgical Outcome 321 John Noel, Ronald Carnemola, and Shampa Chatterjee 24 Proteomics in Understanding the Molecular Basis of Phytochemicals for Health 328 Jung Yeon Kwon, Sanguine Byun, and Ki Won Lee 25 Genomics/Proteomics of NEXT-II, a Novel Water-Soluble, Undenatured Type II Collagen in Joint Health Care 338 Orie Yoshinari, Hiroyoshi Moriyama, Manashi Bagchi, and Debasis Bagchi Part IV Metabolomics 347 26 Harnessing Metabolic Diversity for Nutraceutical Plant Breeding 349 Ashish Saxena and Vicki L. Schlegel 27 Metabolomics and Fetal-Neonatal Nutrition: An Overview 357 Angelica Dessì, Flaminia Cesare Marincola, and Vassilios Fanos 28 Metabolomics, Bioactives, and Cancer 365 Shannon R. Sweeney, John DiGiovanni, and Stefano Tiziani 29 NMR-Based Metabolomics of Foods 379 Takuya Miyakawa, Tingfu Liang, and Masaru Tanokura 30 Cancer Chemopreventive Effect of Curcumin through Suppressing Metabolic Crosstalk between Components in the Tumor Microenvironment 388 Dong Hoon Suh and Yong-Sang Song 31 Metabolomics of Green Tea 397 Yoshinori Fujimura and Hirofumi Tachibana Part V Epigenetics 407 32 The Potential Epigenetic Modulation of Diabetes Influenced by Nutritional Exposures In Utero 409 Jie Yan and Huixia Yang 33 The Time has Come (and the Tools are Available) for Nutriepigenomics Studies 418 Pearlly S. Yan 34 Natural Phytochemicals as Epigenetic Modulators 424 Gauri Deb and Sanjay Gupta Part VI Peptidomics 441 35 Detection and Identification of Food-Derived Peptides in Human Blood: Food-Derived Short Chain Peptidomes in Human Blood 443 Kenji Sato and Daisuke Urado Part VII Nutrigenomics and Human Health 453 36 Use of Omics Approaches for Developing Immune-Modulatory and Anti-Inflammatory Phytomedicines 455 Shu-Yi Yin, Pradeep M. S., and Ning-Sun Yang 37 The Application of Algae for Cosmeceuticals in the Omics Age 476 Nyuk Ling Ma, Su Shiung Lam, and Rahman Zaidah 38 Gut Microbiome and Functional Foods: Health Benefits and Safety Challenges 489 Abhai Kumar, Smita Singh, and Anil Kumar Chauhan 39 An Overview on Germinated Brown Rice and its Nutrigenomic Implications 504 Mustapha Umar Imam and Maznah Ismail 40 Novel Chromium (III) Supplements and Nutrigenomics Exploration: A Review 518 Sreejayan Nair, Anand Swaroop, and Debasis Bagchi Part VIII Transcriptomics 525 41 Transcriptomics of Plants Interacting with Pathogens and Beneficial Microbes 527 Hooman Mirzaee, Louise Shuey, and Peer M. Schenk 42 Transcriptomic and Metabolomic Profiling of Chicken Adipose Tissue: An Overview 537 Brynn H. Voy, Stephen Dearth, and Shawn R. Campagna 43 Nutritional Transcriptomics: An Overview 545 M. R. Noori-Daloii and A. Nejatizadeh 44 Dissecting Transcriptomes of Cyanobacteria for Novel Metabolite Production 557 Sucheta Tripathy, Deeksha Singh, Mathumalar C., and Abhishek Das 45 Inflammation, Nutrition, and Transcriptomics 573 Gareth Marlow and Lynnette R. Ferguson 46 Transcriptomics and Nutrition in Mammalians 581 Carmen Arnal, Jose M. Lou-Bonafonte, María V. Martínez-Gracia, María J. Rodríguez-Yoldi, and Jesús Osada Part IX Nutriethics 609 47 Nutritional Sciences at the Intersection of Omics Disciplines and Ethics: A Focus on Nutritional Doping 611 Nicola Luigi Bragazzi Part X Nanotechnology 623 48 Current Relevant Nanotechnologies for the Food Industry 625 Kelvii Wei Guo References 634 Index 637