Applications of Mass Spectrometry to Organic Sterochemistry

Packed with reviews plus new results from the author's laboratories, the first-of-its-kind work offers a timely and authoritative treatise on the use of mass spectral techniques in organic stereochemistry. Featuring 22 chapters contributed by eminent and active researchers in the field, this unique sourcebook offers comparative information on the use of a variety of mass-spectral techniques to characterize stereoisomers and conformers of both large and small biologically important organic molecules. It also discusses techniques for studying gas-phase conformational equilibria in conformationally mobil systems. Applications of Mass Spectrometry to Organic Stereochemistry will dramatically aid the lab applications of organic, biological, pharmaceutical, and analytical chemists in university and industrial laboratories.

From the Contents: Mass Spectrometric Techniques/ Mass-Spectral Intermediate-Ion Structures/ Stereochemical Effects in the Fragmentation Processes of Saturated and Unsaturated Acyclic Molecular Ions/ Hidden Stereochemistry in the Fragmentation/ Processes of Saturated Cyclic Molecular Ions with One or Two Atoms Between the Functional Group and the Ring/ Stereochemical Effectsin the Fragmentation Processes/ Stereochemical Effects in the Retro-Diels-Alder Fragmentation/ Stereochemical Effects in Mass Spectra and Thermochemistry/ Stereochemical Effects in the Positive- and Negative-Ion Chemical-Ionization Mass Spectra of Stereoisomeric Molecules/ Stereochemical Effects in Ion-Molecule Reactions Studied by Ion-Cyclotron-Resonance Spectroscopy/ Stereochemical Effects in the Mass Spectra of Terpenes and Terpenoids/ Stereochemical Effects Observed for Steroid Compounds