Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways, Volume 1171

Apoptosis is a highly regulated mechanism by which cells undergo cell death in an active way. As one of the most challenging tasks concerning cancer is to induce apoptosis in malignant cells, researchers increasingly focus on natural products to modulate apoptotic signaling pathways. This book reviews the main effects of natural compounds on the different apoptotic signaling pathways, including the intrinsic and extrinsic apoptosis pathways, the NF-kB-mediated pathway, the PI3K/Akt signaling, and other main pathways. Among the topic specially covered are: Effects of natural compounds on cancer cells Natural compounds as inducers of cell death Diet in health and disease Inflammation and cancer Natural compounds as kinase inhibitors Natural compounds in neurodegenerative diseases Natural compounds as inhibitors of ROS NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Part I. Apoptotic Cell Signaling Pathways in Health and Disease Part II. Natural Compounds as Regulators of Cancer Cell Signaling Pathways Part III. Natural Compounds Regulating the Cell Cycle Part IV. Natural Compounds Regulating Apoptotic Cell Signaling Pathways Part V. Dietary Agents in Health and Disease Part VI. Natural Compounds as Inhibitors of inflammation Part VII. MAP Kinase Signaling Pathways Part VIII. Neuroprotection Part IV. Reactive Oxygen Species Part X. Other Types of Cell Death