Water in Biomaterials Surface Science

Presents the latest ideas and research on molecular hydration and hydration forces, and how they determine the interaction between water molecules and biomaterials surfaces. Consisting of three sections; theoretical aspects, analytical aspects and practical applications, it begins by placing the properties of water in a proper molecular perspective. The analytical aspects and practical applications offer a complete overview with new insights into the biomaterials/water interface by: - Discussing the latest approaches to the characterisation of water at interfaces and surface modification of biomaterials - Examining the problems related to the understanding and characterisation of interfacial water - Providing new perspectives of the interfacial interactions between materials and the physiological aqueous environment An invaluable resource for researchers in biomaterials surface science and the biotechnology industry.

Contributors vii Introduction ix M. Morra Theoretical Aspects 1 1 Biological Properties of Water 3 E. A. Vogler 2 Theoretical and Computational Methods of Biomolecular Hydration 25 A. E. Garcia 3 Molecular Dynamics Simulations of Carbohydrate – Water Interactions 53 S. B. Engelsen 4 Statistical Thermodynamics of Fluids with Orientation-Dependent Properties and its Application to Water at Interfaces 91 N.A.M. Besseling 5 Solvation Interactions for Protein Adsorption to Biomaterial Surfaces 127 J. H. Lee, T. Li and K. Park Analytical Aspects 147 6 On the Origin of Water Wetting Terminology 149 E. A. Volger 7 The Evaluation of Electron-Donor and Electron-Acceptor Properties and their Role in the Interaction of Solid Surfaces with Water 183 C Della Volpe and S. Siboni 8 Vibrational Spectroscopy for Water at Interfaces 215 Y. R. Shen 9 Atomic Force Microscope Analysis of Water-Mediated Interfacial Interactions 245 H. J. Butt and V. Franz Practical Applications 267 10 How Water Wets Biomaterial Surfaces 269 E. A. Vogler 11 Super-Hydrophilic Surfaces for Biomedical Applications 291 Y. Ikada 12 Poly(ethylene oxide) Coated Surfaces 307 M. Morra 13 The Role of Water in the Surface Properties of Phospholipid Polymers 333 K. Ishihara 14 Hydrophilic Polysaccharides Coatings 353 M. Morra and C. Cassinelli Index 389