Gastrointestinal Oncology

GASTROINTESTINAL ONCOLOGY Blends quality research findings with advanced educational techniques in a uniquely comprehensive approach Written and edited by leading international experts in the field, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach is an indispensable reference for clinicians, medical practitioners, and trainees involved in the investigation, diagnosis, and treatment of esophageal, gastric, intestinal, colonic, hepatobiliary, pancreatic, and other gastrointestinal tumors. Drawing on the most current evidence-based knowledge, this comprehensive resource reflects the current care of GI cancer patients, enabling effective clinical decision making and patient management. Setting the standard in clinical practice, Gastrointestinal Oncology remains the only truly multidisciplinary reference designed for the diverse team of clinicians responsible for different stages of cancer treatment. Specially structured clinical chapters, each representing a different role in the multidisciplinary team (MDT), allow clear presentation and quick reference of the contents. This is supported by a wealth of high-quality color photographs, line drawings, and diagrams. Now in its second edition, this authoritative reference is fully updated to reflect groundbreaking research in multiple medical fields, including the explorative use of A.I. New sections on palliative care and nutrition are accompanied by new sub-sections on molecular characterization, new targeted small molecule, receptor options, and immunological therapies for each cancer. This edition places renewed emphasis on the most ubiquitous conditions, such as colon cancer, liver cancer, and gastro-esophageal cancer. Covering the oncology of the entire gastrointestinal tract, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach is a must-have reference for the entire MDT, including gastroenterologists, hepatologists, GI surgeons, medical oncologists, radiation therapists, interventional radiologists, pathologists, nutritionists, palliative care and specialist nurses, as well as clinical scientists.

List of Contributors , vii Preface , xvii Foreword , xviii Section I: Upper Gastrointestinal Cancer, 1 1 Epidemiology, Microbiome, and Risk Factors Involved in Carcinogenesis of Esophagus, Gastric, and Intestine, 3 2 Genomics, Molecular Pathology, and Pathology of Esophageal and Gastric Cancer, 23 3 Screening, Surveillance, and Prevention of Esophageal and Gastric Cancers, 42 4 Management of Esophageal Dysplasia and Esophageal Adenocarcinoma, 63 5 Esophageal Squamous Cell Carcinoma, 82 6 Management of Diffuse Gastric Cancer, 116 7 Intestinal-type Gastric Cancer, 120 8 Cancer of the Small Intestine, 139 Section II: Colorectal and Anal Cancer, 145 9 Epidemiology, Microbiome, and Risk Factors Involved in Carcinogenesis of Colorectal Cancer, 147 10 Genomics, Histopathology, and Molecular Pathology of Sporadic and Hereditary Colorectal Cancer, 149 11 Screening, Surveillance, and Prevention for Colorectal Cancer, 170 12 Colorectal Cancer, 181 13 Epidemiology, Pathology, Diagnosis, Prevention, and Management of Anal Cancer, 235 Section III: Hepatobiliary and Pancreas Cancer, 249 14 Epidemiology and Risk Factors of Hepatocellular Carcinoma, 251 15 Pathology, Molecular Pathology, and Genomics of Hepatobiliary and Pancreatic Cancer, 264 16 Screening, Surveillance, and Prevention of Hepatocellular Carcinoma, 271 17 Pancreatic and Biliary Tract Cancers: Risk Factors and Etiology, Screening, Surveillance, and Biomarkers of Detection and Prognosis, 291 18 The Multidisciplinary Management of Primary Hepatocellular Carcinoma, 321 19 Management of Metastatic Liver Cancer, 347 20 Management of Primary Pancreatic Cancer, 386 21 Management of Intrahepatic and Extrahepatic Cholangiocarcinoma, 407 22 Management of Cystic Neoplasms of the Pancreas, 438 Section IV: Specialist Abdominal Cancer Management teams, 455 23 Epidemiology, Pathology, Diagnosis, Prevention, and Management of GI Stromal Tumors and Other GI Sarcomas, 457 24 Neuroendocrine Neoplasms of the Digestive System, 470 25 Epidemiology, Pathology, Diagnosis, Prevention, and Management of Unknown Primary Cancer, 538 26 Diagnosis and Management of Gastrointestinal Lymphomas, 546 27 Palliative and Supportive Medicine in Gastrointestinal Oncology, 561 28 Psychological Oncology and Wellbeing: Wellbeing (part 1) and narrative practices in child palliative care (part 2), 576 29 Nutrition for Cancer Prevention, Adjunctive Cancer Care, and Rehabilitation: Nutrition and Cancer, 587 Cancer – The Road Less Traveled, 591 Index, 593