Statistical Methods in Medical Research

The explanation and implementation of statistical methods for the medical researcher or statistician remains an integral part of modern medical research. This book explains the use of experimental and analytical biostatistics systems. Its accessible style allows it to be used by the non-mathematician as a fundamental component of successful research. Since the third edition, there have been many developments in statistical techniques. The fourth edition provides the medical statistician with an accessible guide to these techniques and to reflect the extent of their usage in medical research. The new edition takes a much more comprehensive approach to its subject. There has been a radical reorganization of the text to improve the continuity and cohesion of the presentation and to extend the scope by covering many new ideas now being introduced into the analysis of medical research data. The authors have tried to maintain the modest level of mathematical exposition that characterized the earlier editions, essentially confining the mathematics to the statement of algebraic formulae rather than pursuing mathematical proofs. Received the Highly Commended Certificate in the Public Health Category of the 2002 BMA Books Competition.

Preface to the fourth edition. 1 The Scope of Statistics. 2 Describing Data. 3 Probability. 4 Analysing Means and Proportions. 5 Analysing Variances, Counts and Other Measures. 6 Bayesian Methods. 7 Regression and Correlation. 8 Comparison of Several Groups. 9 Experimental Design. 10 Analysing Non-Normal Data. 11 Modelling Continous Data. 12 Further Regresson Models for a Continuous Response. 13 Multivariate Methods. 14 Modelling Categorical Data. 15 Empirical Methods for Categrorical Data. 16 Further Bayesian Methods. 17 Survival Analysis. 18 Clinical Trials. 19 Statistical Methods in Epidemiology. 20 Laboratory Assays. Appendix tables. References. Author Index. Subject Index.