Bioprocess Engineering

Divided into four sections, the first and third reflect the fact that there are two types of equipment required in the plant--one in which the actual product is synthesized or processed such as the fermentor, centrifuge and chromatographic columns; and the other that supplies support for the facility or process including air conditioning, water and waste systems. Part two describes such components as pumps, filters and valves not limited to a certain type of equipment. Lastly, it covers planning and designing the entire facility along with requirements for containment and validation of the process.

Partial table of contents: PROCESS SYSTEMS. Fermentor Design (M. Charles & J. Wilson). Large-Scale Animal Cell Culture (G. Smith). Cell Separation Systems (B. Sharma). SYSTEM COMPONENTS. Vessels for Biotechnology: Design and Materials (P. Meyer). Pumps (R. Stover). Instrumentation and Control of Bioprocesses (T. Hartnett). SUPPORT SYSTEMS. Sterilization of Process Equipment (T. Oakley). Biowaste Decontamination Systems (K. Nelson). Heating, Ventilating, and Air Conditioning (HVAC) (D. Dobie). FACILITY DESIGN. Project Planning (J. Boland). Validation of Biopharmaceutical Facilities (R. Baird & P. De Santis). Glossary of Abbreviations. Index.