Polymers in Functional Foods and Drugs

Master the cutting-edge intersection of polymers and medicine with this essential guide, offering both a theoretical understanding and practical applications for innovative drug and food product development. Polymers are showing promise as a solution in a number of fields, including pharmaceuticals, medicine, diagnostics, medical devices, and biotechnology. In the development of drug products, polymers play an important role in nano-formulation development. Also, polymers contribute significantly to functional foods, nutraceuticals, and nutritional supplements. They are used as preservatives, enhancing the shelf life of foods, supplements, and herbal nutraceutical products. This book provides readers with a theoretical understanding and practical applications of polymers in new drug discovery and food product development. It covers a broad spectrum of topics, from fundamental principles and concepts to applications, discussing natural, synthetic, and semi-synthetic polymeric materials. The chapters explore in-depth applications in medical devices, implants, nanosponges, and biological delivery systems, all of which are increasingly important in today’s industry. Discussions on specialized topics, such as natural micropolymers in functional foods and dietary supplements, makes this an essential guide for anyone looking to stay up-to-date with the current trends in pharmaceutical and biotechnology research and development. Readers will find the book: Comprehensively covers natural polymers and their applications in controlled drug delivery; Encompasses interdisciplinary science around polymers in functional food; Explores the delivery of drugs in the current practice of using synthetic polymers. Audience Researchers, scientists, and industry experts working with polymers in the field of pharmaceuticals medicine, diagnostics, medical devices, biotechnology, and nutrition.

Preface xxvii Part 1: Polymers as Carriers in Drug Delivery 1 1 Smart Polymeric Carriers for Efficient Drug Delivery 3 Mohammad F. Bayan and Balakumar Chandrasekaran 2 Polymer-Based Delivery of Novel Drugs 27 Ayah Kamal, Bilal Harieth Alrimawi, Abdulsalam Q. Almashhadani, Shatha Khaled Haif, Amani Marwan Ayyash, Aisha Naim Abdo, Mohamad Dayoob and Mohammad G. Al-Thiabat 3 Recent Advances in Polysaccharide-Based Nanoplatforms for Targeted Cancer Therapy: Innovations and Challenges in Drug Delivery Systems 95 Indiraleka Muthiah, Annie Aglin Antony, Premnath Dhanaraj and Malak Hani Abd Alkarim AlTurk 4 Polymer-Based Drug Release to Enteral and Parenteral Routes 131 Himanshu Sharma, Siddhant Jai Tyagi, Phool Chandra, Anurag Verma, Sumel Ashique, Arshad Farid, Neeraj Mishra, Rashmi Pathak and Afzal Hussain Part 2: Natural Polymers 181 5 Applications of Cellulose-Based Nanoparticles 183 Najlaa Saadi Ismael, Suha Telfah, Iman A. Mansi, Mohammad Abu Nuwar, Aisha Qatawneh and Rand Yasir Alkhammas 6 Applications of Alginate-Based Nanoparticles 209 Aisha Qatawneh, Iman A. Mansi, Suha Telfah, Najlaa Saadi Ismael and Mohammad Abu Nuwar 7 Biodegradable and Biocompatible Natural Polymers in the Drug Delivery System – A New Trend toward the Enhancement of the Therapeutic Efficiencies 245 Rajashri R. Naik, Abeer J.M. Haddad and Ashok K. Shakya 8 Antimicrobial and Wound Healing Effects of Chitosan-Based Nanomaterials 271 Suha Telfah, Mohammad Abu Nuwar, Najlaa Saadi Ismael, Iman A. Mansi and Aisha Qatawneh Part 3: Polymers in Biologicals Delivery 311 9 Applications of Polymers in Delivering Biologics 313 Juhaina M. Abu Ershaid, May Tayyem and Achmad Himawan 10 Polymers in the Biological Sciences 359 Abdel Naser Dakkah, Yousef Abusamra, Mohammad Aldhoun, Adnan A. Dahadha and Walideh Sayed 11 Multiple Natural Polymers in the Delivery of Biological Products 379 Rajwinder Kaur, Varinder Singh, Md Altamash Ahmad, Diksha Choudhary, Arvind Kumar and Sandeep Kumar 12 Polymeric Biomaterials for Medical Implants and Devices 405 Himanshu Sharma, Siddhant Jai Tyagi, Prakhar Varshney, Rashmi Pathak, Sumel Ashique and Afzal Hussain 13 Polymeric Polysaccharides for Biomedical Applications 465 Sathianarayanan Sankaran, Asha Jose, Fatima Jihad Hussein and Wafa’a Kara Mohammed Part 4: Nanopolymers 485 14 Nanopolymers for Smart Drug Delivery Applications 487 Balakumar Chandrasekaran, Mohammad F. Bayan, Layan N. Ghaith, Mays M. Hamdan, Saeed M. Marji and Ashok Kumar Balaraman 15 Polymers in Novel Drug Delivery Systems: Strategies and Enhancement of Vesicular Polymeric Nanocarrier Loaded with Bioactive Phytoconstituents for the Treatment of Rheumatoid Arthritis 511 Vijeta Bhattacharya, M. Alagusundaram, Namrata Mishra, Nem K. Jain, Ramesh Parmar, Balakumar Chandrasekaran and Mohammad F. Bayan 16 Nanosponge as a Dynamic Approach for Targeted Drug Delivery 541 Namrata Mishra, M. Alagusundaram, Vijeta Bhattacharya, Nem Kumar Jain and Rajwinder Kaur Part 5: Polymers in Functional Food 559 17 Applications of Natural Micropolymers in Functional Foods and Dietary Supplements 561 Nour Batarseh References 593 Abbreviations 605 Index 607