Vascular Hemodynamics

The only complete work on vascular hemodynamics Recently, vascular hemodynamics has undergone major advances, resulting from increasingly sophisticated imaging, computational, and clinical research methodologies. The effects of these advances are likely to be profound at both the scientific and clinical levels. Now, Vascular Hemodynamics provides a self-contained treatment of this rapidly advancing topic as it relates to vascular disease and related pathologies in the human body. Utilizing a multidisciplinary approach encompassing engineering, vascular biology, vascular imaging, and clinical practice, the book provides a survey of the basic science and clinical research in hemodynamics of the vasculature. The topics presented involve sophisticated modeling, imaging, and measurement techniques. The text emphasizes both the technical and clinical aspects of the field. Additionally, Vascular Hemodynamics: * Includes a wide variety of models of vascular pathology, including physical models, finite-element models, linear-system models, transmission-line models, and dye-dilution models * Discusses diverse pathologies of the large vessels, the microvasculature, and the systematic vasculature * Brings together a range of imaging modalities related to hemodynamics * Includes both introductory-level and research-oriented material on each topic Vascular Hemodynamics is the only single-text treatment of this important topic, making it a vital reference for researchers and students of bioengineering, radiology, vascular surgery, neurology, nephrology, cardiology, and oncology.

Preface vii Contributors ix 1. Modeling the Vascular System and Its Capillary Networks 1 Thomas H. Dawson 2. Wall Shear Stress in the Arterial System In Vivo: Assessment, Results, and Comparison with Theory 37 Robert S. Reneman, Theo Arts, and Arnold P. G. Hoeks 3. Relating Cerebral Aneurysm Hemodynamics and Clinical Events 63 Juan R. Cebral and Christopher M. Putman 4. Prognostic Significance of Aortic Pulse-Wave Velocity 85 Tine Willum Hansen, Jørgen Jeppesen, and Christian Torp-Pedersen 5. Closed-Loop Modeling of the Circulatory System 94 Carol L. Lucas, Randal Cole, and Ajit Yoganathan 6. Artery Wall Mechanics Determined by Ultrasound 133 Arnold P. G. Hoeks, Evelien Hermeling, and Robert S. Reneman 7. Plaque Mechanics 157 Zhi-Yong Li 8. The Pressure Gradient at Arterial Stenoses: Towards a Noninvasive Measurement 183 Peter J. Yim 9. Measurement of Blood Flow with Phase Constrast Magnetic Resonance Imaging 213 Reza Nezafat and Richard B. Thompson 10. Measuring Cerebral Perfusion Using Magnetic Resonance Imaging 245 Fernando Calamante 11. Cerebral Perfusion Computed Tomography in Stroke 273 Max Wintermark 12. Cerebrovascular Reactivity Changes in Symptomatic Carotid Stenosis 285 Natan M. Bornstein and Alexander Y. Gur 13. Essential Hypertension, Cerebrovascular Reactivity, and Risk of Stroke 299 Cristina Sierra Index 315