The Biological Chemistry of Magnesium

Magnesium ions play a pivotal role in nucleic acid biochemistry, enzyme activation, and many biological systems. This book is the first text to give a unique and comprehensive review of all the major areas of current research interest. It is designed to be useful for students and researchers. Non-specialists will find introductory chapters, and each chapter is fully illustrated and well referenced.

From the Contents: Introduction to the Biological Chemistry of Magnesium Ion/ Physical Methods to study the Biological Chemistry of Magnesium/ Metal Substitution as a Probe of the Biological Chemistry of Magnesium Ion/ Modes and Dynamics of Mg 2+-Polynucleotide Interactions/ Magnesium as the Catalytic Center of RNA Enzymes/ Magnesium-Dependent Enzymes in Nucleic Acid Biochemistry/ Magnesium-Dependent Enzymes in General Metabolism/ Biological Chemistry of Magnesium Ion with Physiological Metabolites, Nucleic Acids and Drug Molecules/ Genetics and Molecular Biology of Magnesium Transport Systems/ Regulation of Cytosolic Magnesium Ion in Hearts