Chemical Biology: Approaches to Drug Discovery and Development to Targeting Disease

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【簡介】 An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences. 【目錄】

Dangerous or Endangered?: Discover the Fascinating Truths of 25 Marine Creatures（精） (1版)

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【簡介】 Dugong. Coffin Ray. Convict Blenny. Vampire Squid. Whale Shark.Do these animals sound dangerous or endangered to you? Because of their common names, bizarre looks or large body sizes, some creatures have a bad reputation and possibly instil fear.But are they really dangerous? Are they endangered, too?Come discover the fascinating facts and stories of 25 marine creatures living across the oceans’ depths, from the shallow intertidal reefs to the deep abyssal trenches. Find out what makes them dangerous, endangered, or both! 【目錄】