Frontier Research in Computation and Mechanics of Materials and Biology: Volume 4

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書名：Frontier Research in Computation and Mechanics of Materials and Biology: Volume 4 作者：Quan Gu 出版商：World Scientific 出版日期：2023-09-01 ISBN：9789811209147 內容簡介 DESCRIPTION The unique compendium teaches beginners how to perform nonlinear finite element (FE) analysis by following a series of step-by-step examples and basic programming method using OpenSees. The scope of the book includes nonlinear FE analyses of reinforced concrete frame shear wall structures, liquefiable soils, soil-structure interaction systems, fluid-solid coupling systems, high-speed railway systems, as well as introduces the sensitivity, reliability, optimization, peridynamic (PD) analysis, and the integration of OpenSees with other softwares. This must-have reference also teaches users how to program by adding simple material and element models, as well as PD algorithms in OpenSees. Sample Chapter(s) Preface Chapter 2: A Simple Structural Analysis Example Chapter 16: Adding an Elasto-Perfect-Plasticity Material in OpenSees Contents: Introduction to OpenSees Application: Download and Run A Simple Structural Analysis Example Introduction to Tcl Syntax Frame Structure Analyses Analyses for Reinforced Concrete Shear Walls Soil–Structure Interaction (SSI) System Fluid–Solid Coupling Numerical Analyses of Soil Liquefaction Numerical Optimization Coupling OpenSees with Other Software Using the Client–Server Technique Response Sensitivity Analysis Based on Direct Differentiation Method (DDM) Structural Analysis Based on Bond-Based Peridynamics (BPD) A Wheel–Rail Interaction Element for High-Speed Railway System Reliability Analysis Introduction to OpenSees Programming: Downloading the Package and Building OpenSees Source Code Adding an Elasto-Perfect-Plasticity Material in OpenSees Adding a New Element in OpenSees Implementing State-Based Peridynamics (SPD) in OpenSees Readership: Professionals, academics, researchers and graduate students in civil engineering, earthquake engineering and engineering mechanics.

Frontiers in Boron-based Medicinal Chemistry

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Boron has long occupied a privileged role in chemistry (as a catalyst component) and human health (as a micronutrient). In 1951, boron science took a momentous leap forward with its application in clinical cancer research. The seventy or so years since have witnessed exciting developments in the technology now known as Boron Nuclear Capture Therapy (BNCT), a binary form of radiotherapy that lethally combines two separately non-lethal constituents: a boron-based radiosensitizer and non-ionizing neutron radiation. Frontiers in Boron-based Medicinal Chemistry is a one-stop resource on the current state of BNCT and promising works in the pipeline. It begins with an introduction to general boron chemistry, with extensive discussion on important boron compounds including boranes, boronic acids, carboranes, and FDA-approved boron drugs. Chapter 2 looks at BNCT in clinical trials, while Chapter 3 describes emerging next-generation agents such as boron-based nanoparticles and dendrimers. The penultimate chapter summarizes the currently used and emerging imaging techniques in BNCT, namely, PET, CT, MRI and fluorescence microscopy. The book concludes with a technically heavy chapter on neutron sources and dosimetry. The cutting-edge information contained in this authoritative volume will be a valuable resource for all those involved in mankind's endless struggle against cancer. Sample Chapter(s) Preface Chapter 3: Dendritic and Nanostructured Boron Compounds for Boron Neutron Capture Therapy Contents: Preface About the Editor General Boron Chemistry and Medicinal Applications: Elemental Boron General Boron Chemistry The Preparation of Elemental Boron Boron Compounds with Important Influence Boron Compounds for Pharmaceutical Applications References Boron Neutron Capture Therapy in Clinical Trials: BNCT in Cancer Therapy Importance of the Boron Drug in BNCT New Boron Agents Developed for BNCT Conclusions and Perspectives References Dendritic and Nanostructured Boron Compounds for Boron Neutron Capture Therapy: Introduction to Boron Neutron Capture Therapy Introduction to Nanomaterials and Dendrimers Advantages of Nanomaterials and Dendrimers BNCT for Treatment of Cancer Conclusion References Application of Theranostic Technology in Boron Neutron Capture Therapy: Introduction Magnetic Resonance Imaging in BNCT Positron Emission Tomography/Computed Tomography Scanning in BNCT Fluorescence Imaging in BNCT Summary and Outlook References Developments in Neutron Sources for Boron Neutron Capture Therapy: The Neutron Neutron Sources for BNCT Dosimetries in BNCT Treatment Process References Index Readership: Industrial scientists, academics, and graduate students in medicinal/pharmaceutical chemistry, drug design/development, nanomedicine and cancer research. Chapter 4 will be of interests to radiologists and those in nuclear medicine, while Chapter 5 will appeal to biomedical engineers and medical physicists.