The AFS Textbook of Foregut Disease (1版)

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The AFS Textbook of Foregut Disease serves as a comprehensive guide of information covering the fast-evolving field of foregut disease. This textbook is designed as a partnership between gastroenterologists & gastrointestinal surgeons with an understanding that an essential component of moving forward in this field is through collaboration. This AFS textbook has been developed by the American Foregut Society, a premier society for foregut disease and all chapters are written by experts in the field. Readership is intended for gastroenterologists, GI and thoracic surgeons, gastroenterology and general surgery residents and fellows, medical students, and integrated health members that manage foregut disease. All chapters follow an organized format that contains many graphs, tables, intraoperative photographs, and illustrations of techniques. This textbook provides the most up-to-date scientific information and will be the definitive resource to guide both the diagnosis and management of foregut disease for years to come.

Doppler Ultrasound in Obstetrics and Gynecology (3版)

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This book, now in a comprehensively revised and expanded third edition, covers the full spectrum of applications of Doppler ultrasound within Obstetrics and Gynecology. The current standards of practice in Doppler ultrasound are described, and information presented on the most recent developments in clinical practice and technology. The basic and physical principles of Doppler ultrasound are also clearly explained. Among other topics, the chapters on obstetric applications address the use of Doppler for fetal examination, including investigation of the fetal cerebral circulation; Doppler echocardiography of the fetal heart; and the role of Doppler in cases of post-term pregnancy and multiple gestation. The final part of the book focuses on the use of Doppler ultrasound in patients with gynecologic conditions, including ectopic pregnancy, infertility, benign disorders, and malignancies. Written by distinguished experts in the field, this superbly illustrated book will be a must-havereference for maternal-fetal medicine specialists, obstetrician-gynecologists, radiologists, and sonographers and will also be of value for researchers in the field.

Cardiovascular Neuroendocrinology (1版)

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The cardiovascular system and the neuroendocrine system are integrated at multiple levels. This integration is key to normal physiological function. Further, it adapts to accommodate changes related to aging, the organism’s reproductive state, or physiological challenges. This type of adaptability, or plasticity, also can contribute to pathophysiology when these systems are stressed. This volume discusses how neuroendocrine systems influence cardiovascular function in health and disease. The first section provides detailed background information on neuronal and neuroendocrine control of cardiovascular function. This is followed by chapters highlighting the cardiovascular role of neuroendocrine hormones in regulating physiological states, such as pregnancy, and the effects of biological sex on vascular function. The influence of exercise, stress, psychology, and aging on cardiovascular function and dysfunction, and the possibility of therapeutically targeting the neuroendocrine axis for the treatment of cardiovascular disease are discussed in the final section of the book. This book is of relevance for students, trainees and established researchers alike who are seeking for an overview on the neuroendocrine control of cardiovascular function and disease. This is the fourteenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Advancements and Innovations in OMFS, ENT, and Facial Plastic Surgery (1版)

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​This book will cover updated practices and cutting-edge innovations pertinent to advanced Oral & Maxillofacial Surgeons, Otolaryngologists (Head and Neck Surgeons), and Facial Plastic Surgeons. Each chapter will review and update the reader on advancements in procedures and technologies in head and neck surgery. The authors are world-renowned experts in their respective fields who are keen to share their extensive experience and preferred approaches. Chapters will cover: Reviewing current techniques and highlighting future innovations and technologies pertaining to oral, head, and neck surgery. Illustrating ways to formulate specific treatment plans for the management of complex ailments and defects of the head and neck region. Developing specific treatment plans for the reconstruction of complex structures. Updating reader knowledge on both current and up-and-coming innovative procedures. Discussing the science underlying current and next-generation technologies. This book is intended for all oral and maxillofacial surgeons, head and neck surgeons, and plastic and reconstructive surgeons who wish to increase their knowledge on the latest modalities of maxillary and mandibular reconstruction.

Drug Development in Psychiatry (1版)

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The book reviews clinical trial methodology as it pertains to drug development in psychiatry. The reader will understand the process of drug development in psychiatry from discovery through marketing with the help of clinically relevant examples. The reader will appreciate the history of drug development in psychiatry dating back to the era of serendipitous discovery and culminating in an era of new and highly focused targets. Readers will understand how drug development in psychiatry has changed and adapted with the discovery of novel mechanism of action drugs. Novel drugs and disease targets have changed the way developers and regulatory agencies think about clinical trial methodology. The book elucidates how biomarkers, genetics and advances in neuroscience and neuroimaging have influenced drug development approaches, which will ultimately change the practice of psychiatry. The book will be broken down into the following sections: a. Prior to the 1960s - Drug discovery by chance observation b. The last 50 years – refined targeting of CNS drugs without the discovery of mechanistically new drugs c. The future – the discovery and development of mechanistically new drugs. The examination of new targets, genetics and biomarkers.