應用生物藥劑學與藥物動力學 (Applied Biopharmaceutics ＆ Pharmacokinetics 6/e) (2版)

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書名：應用生物藥劑學與藥物動力學 作者：劉正雄 出版社：合記 出版年份：2015 條碼：9789863411727 簡介： 本書自首版至今30餘年，期間經六次大幅改版，內容主要包括藥學的基礎理論、藥品的開發，以及臨床藥理實務等相關資訊。讀者不僅可藉由書中原始數據導出藥物動力學的模式及參數，並應用於劑量的設計和評估規劃外，對於藥品的安全性與有效性的提昇也有助益。除此之外，本版新納入的議題有藥品開發與藥物療法的應用新知，以及當前的藥理學發展趨勢，是目前國內外藥學相關系所採用的必備教科書，也是藥學相關執業人員的重要參考用書。 原著序： 應用生物藥劑學與藥物動力學第六版的出版，表示它刊已行了30年以上。我們感謝讀者在過去多年來的忠實與協助性建議。如同先前的各版，我們希望繼續維持我們原有的範疇與目標。 本教科書整合了基礎科學原理與藥物產品開發及臨床藥理實務。 主要目標是對讀者提供可應用於藥物產品開發與藥物療法的生物藥劑學與藥物動力學方面基礎與實務之知識，本教科書此次的修訂和更新的版本仍保有原先特色，就是教導可應用在瞭解對安全及有效藥物療法必要的有關體內藥物輸送之複雜問題的基本概念。 主要的讀者是主修藥物科學課程、學習藥物動力學和生物藥劑學的藥學系學生。本教科科書可以滿足這些學生在單獨或合併課程，應這些主題課業之需要。本書的次要讀者是在從事藥劑學、生物藥劑學及藥物動力學研發的科學家。 這一版有許多的改進。 ˙本章目標 (Chapter Objective) 加於每一章開頭 ˙本章摘要 (Chapter Sumrnary) 置於每一章結尾 ˙常見問題 (Frequently Asked Questions) 分散在各章內，幫助學生注意關鍵的概念。 ˙大多數的章節都已修訂，以反映當今我們在藥物體內動向、藥效學及藥物療法之相關知識。 ˙藥物轉運者，CYP逐漸被重視，以及藥物遺傳學對於長期藥物反應和其他相關議題之影響已經更新，以反映當代的知識及藥物動力學∕藥效學應用在藥物療法。 ˙第15章已擴充，重定標題為「藥物產品性能，體內試驗：生體可用率與生體相等性」，以反映生體相等性作為藥物產品性能體內試驗的測定之考量，而且生體相等性在商標名與俗名藥物產品的開發上都相當重要。 ˙第16章在這一版的標題是「藥物產品品質與生物藥劑學對臨床功效的影響」。本章說明安全性與有效生風險的類型及各種預防方法，包括藥物產品品質與藥物產品性能。 ˙此外，產品依設計的品質 (quality-by-design, QbD) 概念可以應用於改善對於藥物產品安全與有效性重要的關鍵品質屬性 (critical quality attributes)。 ˙納入實例與例題以鼓勵學生將原理應用在病人照護及藥物諮詢的場合。 ˙強調主動學習與基於成效的目標。 Leon Shargel Susanna Wu-Pong Andrew B.C.Yu

Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics (8版)

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【少量特別書籍 若無貨可能須等候5-7日以上 因”客制特別調書不收退貨” 可接受在下單】 Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics (IE) 951-6960/9781260469608 ISBN 9781260469608 作者/出版社 *Ducharme／McGraw-Hill 出版年代/版次 2022 ／ 8 重量：1.68kg 　頁數：1010 裝訂：精裝　開數：24 x 19.1 cm　印刷：雙色 The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years.  This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas.  Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include:   oPhysiological factors related to drug absorption oApproaches to pharmacokinetics and pharmacodynamics calculations  oNovel and complex dosage Forms oClinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products oPharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions

INTRODUCTION TO APPLIED NUMERICAL ANALYSIS, AN

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his book is based on lecture notes for a numerical analysis course designed mainly for senior undergraduate students majoring in mathematics, engineering, computer science and physical sciences. The book has two overarching goals. The first goal is to introduce different available numerical procedures for finding solutions to linear equations, roots of polynomial equations, interpolation and approximation, numerical differentiation and integration, differential equations, and error analysis. The second goal is to translate theory into practice through applying commonly used numerical methods in mathematics, physical sciences, biomedical sciences, and engineering. This book was crafted in an informal and user-friendly manner to motivate the study of the material being covered. Ample figures and numerical tables are presented to enhance the reader's ease of understanding of the material under consideration. Sample Chapter(s) Preface Chapter 7: Boundary Value Problems Contents: Preliminaries Solution of Linear System of Equations Roots of Nonlinear Equations Polynomial Approximation and Interpolation Differentiation and Integration Initial Value Problems Boundary Value Problems Partial Differential Equations Readership: Undergraduate students in Mathematics, Statistics, Physics, Engineering and Computer Science, biomedical, and any Course dealing with numerical calculations and computations.