Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders (1版)

類似書籍推薦給您

This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned aboutthese crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines,and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.

The Role of Natural Antioxidants in Brain Disorders (1版)

類似書籍推薦給您

Oxidative stress and neuroinflammation are considered causative factors in various neurological disorders such as Parkinson’s and Alzheimer’s diseases. Antioxidants are chemicals that bind with oxidative species and nullify their effect from causing damage to biological molecules. Endogenous antioxidants are produced by our body, however most of them are obtained from external sources, primarily through diet, called dietary antioxidants. Major sources of antioxidants are brightly colored fruits, vegetables, cereals, legumes, and herbs. Other very effective sources are berries, green tea, and dark chocolate. These compounds have the potential to hinder neurodegeneration, reduce neuronal death and improve memory as well as cognitive functions. Based on the complex nature of antioxidants and oxidative stress, particular antioxidants such as vitamin E, vitamin C or β-carotene are beneficial in protecting cells, organs and tissues against oxidative damage. The Role of Natural Antioxidants in Brain Disorders describes various neuroprotective effects and their physiological phenomenon mediated by antioxidants to maintain and regulate the general health biomarkers against brain disorders. The important role of antioxidants, diet and lifestyle in managing brain disorders is covered, as is their use in conjunction with conventional therapies against oxidative stress. Both exogenous and endogenous antioxidants are explored in full. By focusing on the role of oxidative stress as a triggering mechanism for various brain disorders and the use of antioxidant foods in conjunction with traditional therapies in combating and preventing them, this is a valuable source for researchers in food science, nutrition, health science and physiology.

Neuroradiology of Brain Tumors (1版)

類似書籍推薦給您

While several books describing imaging of brain tumors from MR acquisition techniques to differential diagnosis are written by different contributors and present chapters with different styles and design, this book illustrates a unique vision and structure putting together modern molecular classification of brain tumor with modern neuroradiology. After an introduction on general imaging features of brain tumors the book explores each different tumor according to 2021 WHO classification, distinguishing however between adult and pediatric tumors, being the epidemiology substantially different between these two groups. The approach is schematic with few essential information on epidemiology, genetics, clinical features, location and prognosis, followed by a detailed description of imaging features with a large number of examples. Figures are mainly put together with the same modality considering all the different MR techniques as well as CT when it can be useful. Each figure provides T1, T2, FLAIR, DWI, ADC, perfusion imaging techniques, spectroscopy and post contrast study. Some examples of Amide Proton Transfer (APT) technique are provided as well. At the end of each chapter a scheme summarizes the different appearance of the tumor in any different sequence. This book will be an invaluable tool for neuroradiologists, radiologists, neurosurgeons, neurologists, pediatricians, and pathologists.

Mind, Brain and Education (1版)

類似書籍推薦給您

This book, Mind, Brain and Education, comprises selected topics from Neurology and Psychiatry, showing both their common ground and their differences. A special emphasis is given to the role of scientific gathering with the Mind & Brain Congress as a platform for educating younger colleagues and widening their perspectives in the field of both disciplines. With the new discipline of Psychoneuroendocrinoimmunology (PNEI) and its translation to clinical practice, our long-standing comprehensive approach to the interrelation and bridging of the mind and the brain contributes to a better understanding of this challenging topic. The reader can find new facts showing how diseases are the result of an alteration at the bio-psycho-social level. PNEI provides knowledge about the biological dynamics of conventional medicine and of the importance of lifestyle changes in order to fight disease.

Sex Differences in Brain Function and Dysfunction (1版)

類似書籍推薦給您

Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mentalhealth and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.