【中文翻譯書】
書名:藥物化學 第三版
原文書名:An introduction to medicinal chemistry 3/E
原文作者:Graham L. Patrick
中文譯者:王志鉦
ISBN:9789576169229
目次
內容摘要
專欄清單
字母縮寫與簡稱
藥物的分類
藥物的命名
PART A 藥物藥效學與藥物動力學
1藥物與藥化學家
2為什麼和為何藥物會產生作用
3蛋白質作為藥物作用標靶
4蛋白質作為藥物作用標靶:酵素
5蛋白質作為藥物作用標靶:受體
6蛋白質作為藥物作用標靶:受體結構與訊息傳遞
7 核酸作為藥物標靶
8 藥物動力學和相關主題
PART B 藥物的發現、設計與發展
9藥物的發現:先導化合物的發現
10 藥物設計:優化作用標靶交互作用
11藥物設計:對作用標靶的優化接近
12 藥物的發展
PART C 商業工具
13 構效量化關係
14組合式合成
15電腦在藥物化學上的應用
PART D 藥物化學上選擇的主題
16 抗菌劑
17抗病 藥劑
18 抗癌藥物
19膽鹼性藥、抗膽鹼性藥物和抗膽鹼酯
20腎上腺素性神經系統
21鴉片類止痛劑
22抗潰瘍藥物
附錄一 必須胺基酸
附錄二 標準基因密碼
附錄三 構效量化關係的統計資料
附錄四 神經的作用
附錄五 微生物
附錄六 藥物與商品名
名詞解釋
一般深入閱讀
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