The Nitro Group in Organic Synthesis

The most useful reactions of organonitro compounds in organic synthesis Compounds containing nitro groups are useful intermediates for the synthesis of natural products and other complex organic molecules. The Nitro Group in Organic Synthesis focuses on reactions that proceed under mild conditions, important functional groups that can be synthesized by conversion of nitro groups, and the stereoselectivity of reactions of nitro compounds. These issues are of great importance to practicing researchers in today's pharmaceutical, agrochemical, and fine chemical industries. The Nitro Group in Organic Synthesis also emphasizes environmentally-friendly methods for nitration, the importance of aliphatic nitro compounds, and modern preparation of nitro compounds. Other topics discussed include: * Henry reaction * Asymmetric Michael addition * Alkylation, acylation, halogenation, and related reactions of RNO2 * Substitution and elimination of NO2 and RNO2 The Nitro Group in Organic Synthesis is a useful resource for researchers and students in organic and medicinal chemistry.

Series Foreword. Preface. Acknowledgments. Abbreviations. Introduction. Preparation of Nitro Compounds. The Nitro-Aldol (Henry) Reaction. Michael Addition. Alkylation, Acylation, Halogenation of Nitro Compounds. Conversion of Nitro Compounds into Other Compounds. Substitution and Elimination of NO_2 in R-NO_2._ Cycloaddition Chemistry of Nitro Compounds. Nucleophilic Aromatic Displacement. Synthesis of Heterocyclic Compounds. Index.