Baculovirus Expression Systems and Biopesticides

Baculovirus Expression Systems and Biopesticides Edited by MichaelL. Shuler, H. Alan Wood, Robert R. Granados, and Daniel A. HammerBaculovirus Expression Systems and Biopesticides provides anintegrated perspective on the use of the continually evolvingbaculovirus-insect cell system in the production of recombinantproteins and genetically engineered pesticides. Divided into threemain sections--Developing Effective Virus-Insect Culture Systems,Bioreactor Design and Scale-Up Issues, and Commercial Applicationof Insect Cell Culture--the book, written by highly regardededitors in the field, describes: * The molecular biology and genetics of baculoviruses * The use of baculoviruses as expression systems * Principles and methods for small- and large-scale insectcultures * The use of wild type and genetically engineered baculoviruses asviral pesticides The breadth of coverage in Baculovirus Expression Systems andBiopesticides will meet the needs of molecular biologists, chemicalengineers, biotechnologists,virologists, and entomologists.

Partial table of contents: DEVELOPING EFFECTIVE BACULOVIRUS-INSECT CULTURE SYSTEMS. Insect Cell Culture Methods and Their Use in Virus Research (R.Granados & K. McKenna). Comparison of Mammalian and Insect Cell Cultures (M. Shuler). Development and Testing of Genetically Improved BaculovirusInsecticides (H. Wood). BIOREACTOR DESIGN AND SCALE-UP ISSUES. Overview of Issues in Bioreactor Design and Scale-Up (R. Taticek,et al.). The Effect of Hydrodynamic Forces on Insect Cells (J.Chalmers). COMMERCIAL APPLICATION OF INSECT CELL CULTURE. Baculovirus-Mediated Production of Proteins in Insect Cells:Examples of Scale-Up and Product Recovery (M. Silberklang, etal.). Index.