Enzyme Kinetics

Covers enzyme kinetics from its most elementary aspects to such modern subjects as steady-state, multi-reactant kinetics and isotope exchange. Offers an understanding of the behavior of enzyme systems and the diagnostic tools used to characterize them and determine kinetic mechanisms. Illustrates and explains current subjects such as cumulative, concerted and cooperative feedback inhibition and metal ion activation.

Kinetics of Unireactant Enzymes. Simple Inhibition Systems. Rapid Equilibrium Partial and Mixed-Type Inhibition. Enzyme Activation. Rapid Equilibrium Bireactant and Terreactant Systems. Multisite and Allosteric Enzymes. Multiple Inhibition Analysis. Steady-State Kinetics of Multireactant Enzymes. Isotope Exchange. Effects of pH and Temperature. Appendix. Index.