Wound Healing

A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

List of Contributorsvii 1 Stem Cell Regeneration and Repair – Overview 1 Clement D. Marshall, Alessandra A. Moore, Michael T. Longaker, and H. Peter Lorenz 2 Cadherins as Central Modulators of Wound Repair 15 Melissa Crawford and Lina Dagnino 3 Tight Junctions and Cutaneous Wound Healing 31 Thomas Volksdorf and Johanna M. Brandner 4 The Role of Microvesicles in Cutaneous Wound Healing 43 Alexandra Laberge and Véronique J. Moulin 5 Wound Healing and Microenvironment 67 Elgin Türköz Uluer, Hafize Seda Vatansever, and Feyzan Őzdal Kurt 6 Wound Healing and the Non-cellular Microenvironment 79 Hayley S. Ramshaw, Jasreen Kular, and Michael S. Samuel 7 Contribution of Adipose-Derived Cells to Skin Wound Healing 89 Barbara Gawronska-Kozak, Joanna Bukowska, Xiying Wu, Amy Lin Strong, Trivia Frazier, Bruce A. Bunnell, and Jeffrey M. Gimble 8 Role of Bone Marrow-Derived Stem Cells in Wound Healing 103 Feyzan  Özdal Kurt, Hafize Seda Vatansever, and Elgin Türköz Uluer 9 Role of Vitamin D and Calcium in Epidermal Wound Repair 113 Daniel D. Bikle, Chia-ling Tu, and Yuko Oda 10 Oral Mucosal Healing 125 Luisa A. DiPietro and Megan Schrementi 11 Role of Adipose-Derived Stem Cells in Wound Healing: An Update from Isolation to Transplantation 133 Selami Demirci, Ayşegül Doğan, and Fikrettin Şahin 12 The Hair Follicle as a Wound Healing Promoter and Its Application in Clinical Practice 149 Francisco Jimenez, María Luisa Martínez, Eduardo Escario, and Ander Izeta 13 Impaired Wound Healing in Diabetic Ulcers: Accelerated Healing Through Depletion of Ganglioside 167 Duncan Hieu M. Dam, Sophia A. Jelsma, and Amy S. Paller 14 Inflammation in Wound Repair: Role and Function of Inflammation in Wound Repair 177 Amanda S. MacLeod and Jeffery T. Kwock 15 Inflammation, Wound Healing, and Fibrosis 195 Shibnath Ghatak, Vincent C. Hascall, Ricardo Moreno Rodriguez, Roger R. Markwald, and Suniti Misra 16 The Potential Role of Photobiomodulation and Polysaccharide-Based Biomaterials in Wound Healing Applications 211 Heidi Abrahamse, Sathish Sundar Dhilip Kumar, and Nicolette Nadene Houreld 17 Is Understanding Fetal Wound Repair the Holy Grail to Preventing Scarring? 225 Olivier A. Branford and Kerstin J. Rolfe 18 Inflammation and Cancer 239 Suniti Misra, Vincent C. Hascall, Roger R. Markwald, Paul E. O’Brien, and Shibnath Ghatak Index 275