X-ray crystallography has long been a powerful tool in the elucidation of the three-dimensional structures of small molecules and macromolecules. However, despite its power, it is a technically challenging subject that those new to the technique often find daunting. An ideal primer for students encountering the technique for the first time, Principles of X-ray Crystallography provides a clear, succinct guide to the three-dimensional world of molecules. Featuring a lucid and direct writing style, real-life examples, diagrams, exercises, and activities, this unique text engages students in visualizing three-dimensional structures, rather than overwhelming them with excessive detail. Author Li-ling Ooi explores both the theoretical principles on which the technique is based and the practice of gathering and analyzing crystallographic data, offering a balanced, well-rounded account of the field. Drawing on valuable teaching experience, Ooi employs a tutorial approach--including self-test exercises and hands-on activities--that leads students through key concepts in a carefully structured and evenly paced manner. The text encompasses aspects of both small molecule and macromolecular crystallography, highlighting the similarities and differences between the two. A companion website features resources for students--a library of annotated web links and data sets related to topics discussed in the book--and instructors--downloadable figures from the book in electronic format and PowerPoint slide sets for each chapter.