Skeletal Muscle Stem Cells (1版)

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This volume looks at the latest technologies and methods--combined with new genetic tools available in animal models--used in this constantly evolving field. The chapters in this book are organized into three sections: Section one covers muscle stem cells and progenitor cells; Section Two discusses animal models for muscle stem cells and regeneration; and Section Three explores bioinformatics and imaging analysis for muscle stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Skeletal Muscle Stem Cells and Regeneration: Methods and Protocols is a valuable tool for all researchers looking to expand their knowledge on skeletal muscle growth, repair, degeneration, aging, and regenerative medicine.

SCIENCE, POLITICS, STEM CELLS AND GENES

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Is there a way to fight back against "incurable" disease? California thought so — and put its money where its mind was — three billion dollars' worth! And when that was gone, how about five and a half billion dollars more — to build and expand the California Institute for Regenerative Medicine? For some, science excites; it is the great adventure, to challenge the impossible: like a real-life battle with a giant squid, or the proposed disassembly of the Eiffel Tower, or ejecting from a jet in the sky, from a height greater than Mount Everest. For others, regenerative medicine is a mystery — could the urge to do murder have a genetic cause — which might be reduced? And for everyone, there is the fight to protect our loved ones' lives— 133 million of us, suffering from chronic disease — from America alone, a colossal cost of 3 trillion dollars last year. An epic battle, "Science, Politics, Stem Cells and Genes: CALIFORNIA'S WAR ON CHRONIC DISEASE" takes the reader behind the scenes. An award-winning teacher, Reed shares science in stories — including the systematic assault on Alzheimer's disease, cancer, autism, epilepsy, liver failure, schizophrenia, obesity, stroke, sickle cell, arthritis, blindness, paralysis, kidney failure, ALS, aging, and much, much more. Readers can expect a greater understanding of the intricate adventure of stem cell research, as well as the political wrestling it took to make progress possible — that California's effort may benefit the world. From early research to clinical trials, America should take pride in the accomplishments of the California Institute for Regenerative Medicine. Read on. Sample Chapter(s) Foreword 1: The Golden State, and Stem Cell Possibilities Contents: The Golden State, and Stem Cell Possibilities The Dream I Wish Had Not Come True The Shot Policeman and the Walk-again Rat The Importance of Pizza (Boxes) Please Help Change the World! "But Where Do You Keep the Babies?" Sued by an Embryo? Where I Left My Heart Muotri's Robot The Loss of a Friend, and Two Shark Stories Killer in My Classroom Dr Larry vs Alzheimer's Making a Hemo Substitute? Tarzan and the Obesity Demon Before the Lightning Strikes The Man Who Fell from the Sky Tunnels Grampa and the Lion Diagnosis and Decisions The Possibility of Cure Gloria's Last Request The Pope and the Whale The Passing of Gloria The Half-Empty House A Science Adventure Down and Out? Running in the Dark R U Latin-X? The Multiplicity Disease Fighting Forward Against the Plague Of Tigers, Pain and Sickle Cell How Many Chronic Diseases Do You Have? A Legacy of Cure A Teenage Gorilla — And the Citizen's Initiative? Protect the Nerves! Of Ninja Women Warriors, and The Fight Against Disease Son of Bob Strikes Back The Villain in Aging? 133 Million Reasons for Cure — and One More "And Care for Him, Who Shall Have Born the Battle" ... An Appreciation of Asian-American Scientists Of Crocodiles, and The Cost of Losing A Romance of Kidney Failure? Champions All Mud and Dust, Fire and Flood Nearing the Top of the Mountain Supply to the Eyes? How Roman Gets Up in the Morning A Scientist's Life for You? But Can We Afford iIt? Incurably III — for Just One Day? The Second-Most Important Matter on the Ballot Staying Out of Politics? A Child's Life Disassembling the Eiffel Tower? Your California College — Was It Helped by CIRM? What We Have Won Unfinished Business A Christmas Poem Statement from Maria T Millan, President/CEO California Institute of Regenerative Medicine An Interview with Bob Klein Readership: Stem cell researchers; patient advocates, sickle-cell sufferers, students, science teachers, scientists in biomed field, parents of children with disabilities, young people wanting a career in biomed.

PRINCIPLES OF SOLAR CELLS

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How does a solar cell work? How efficient can it be? Why do intricate patterns of metal lines decorate the surface of a solar module? How are the modules arranged in a solar farm? How can sunlight be stored during the day so that it can be used at night? And, how can a lifetime of more than 25 years be ensured in solar modules, despite the exposure to extreme patterns of weather? How do emerging machine-learning techniques assess the health of a solar farm? This practical book will answer all these questions and much more. Written in a conversational style and with over one-hundred homework problems, this book offers an end-to-end perspective, connecting the multi-disciplinary and multi-scale physical phenomena of electron-photon interaction at the molecular level to the design of kilometers-long solar farms. A new conceptual framework explains each concept in a simple, crystal-clear form. The novel use of thermodynamics not only determines the ultimate conversion efficiencies of the various solar cells proposed over the years, but also identifies the measurement artifacts and establishes practical limits by correlating the degradation modes. Extensive coverage of conceptual techniques already developed in other fields further inspire innovative designs of solar farms. This book will not only help you to make a solar cell, but it will help you make a solar cell better, to trace and reclaim the photons that would have been lost otherwise. Collaborations across multiple disciplines make photovoltaics real and given the concern about reducing the overall cost of solar energy, this interdisciplinary book is essential reading for anyone interested in photovoltaic technology. Request Inspection Copy Sample Chapter(s) Preface Chapter 1: Overview: Sun, Earth, and Solar Cell Contents: Preface Acknowledgments Overview: Sun, Earth, and Solar Cell Thermodynamics of Solar Cells: A Two-level Solar Cell Thermodynamic Limits of 3D Solar Cells Thermodynamic Limits of Tandem, Bifacial, and Concentrator Solar Cells Self-heating of Solar Cells Limits of Light Absorption Transport Physics of Three Types of Cells: Physics of Typical Solar Cells Organic Solar Cells Physics and Universality of Shunt Distribution Physics of Series Resistance of Solar Cells and Modules Design of a PV System: Panels, Farms, and Storage: System Integration of Solar Modules Design of Solar Farms Design of a Vertical Solar Farm Solar Farms: Practical Perspectives Storing Energy from Solar Cells Reliability and Characterization of Solar Cells: Levelized Cost of Electricity Highlights the Importance of Efficiency and Reliability of Solar Modules Soiling vs. Cleaning: An Optimization Problem A Transient Partial Shadow May Cause Permanent Damage Dangerous Hotspots are Caused by Weak Diodes and Strong Shunts Photodegradation of Solar Cells Due to UV Exposure Light-induced Degradation in Solar Cells Potential-Induced Degradation is a Serious Reliability Issue Humid Environment Causes Electrode Corrosion Physics of Glass, Cell, and Backsheet Cracking: Mechanical Reliability of Solar Modules Qualification of Module Reliability Predicting the Lifetime of Solar Farms Inverse Modeling and Monitoring the Health of a Solar Farm The Road Ahead ... Index Readership: Advanced undergraduate to beginning graduate students in physics and engineering to researchers and material scientists working in academia, industry, and national laboratories across the world.